Sildenafil

Why people explore this treatment

• ■Treatment of erectile dysfunction in men, as diagnosed by a provider

What It Is

Sildenafil is an FDA-approved prescription medication belonging to a class of drugs called PDE5 inhibitors. It is approved for the treatment of erectile dysfunction (ED) in men.

How It Works

Sildenafil works by increasing blood flow to the penis in response to sexual stimulation. It does this by inhibiting the PDE5 enzyme, which helps maintain the blood flow necessary for an erection.

Clinical Uses

• ■Treatment of erectile dysfunction in men, as diagnosed by a provider

Available Formulations

• ■Oral tablet
• ■Multiple dose strengths

Potential Benefits

• ■May help achieve and maintain an erection in response to sexual stimulation
• ■Taken as needed before activity

Risks & Considerations

• ■Not safe with nitrate medications
• ■Requires cardiovascular evaluation
• ■Not for recreational use

Potential Side Effects

• ■Headache
• ■Flushing
• ■Indigestion
• ■Nasal congestion
• ■Visual disturbances (rare)
• ■Prolonged erection (seek immediate medical attention)

Who May Not Be a Candidate

• ■Patients taking nitrates
• ■Patients with severe cardiovascular disease
• ■Patients with severe liver impairment
• ■Patients with recent stroke or heart attack

Monitoring & Labs

• ■Blood pressure
• ■Cardiovascular assessment as indicated

Regulatory / Clinical Status

FDA-approved for the treatment of erectile dysfunction.

How It Is Administered

Sildenafil is taken orally, typically as needed before sexual activity. Your provider will determine the appropriate dosage and usage instructions.

What to Discuss With Your Provider

• ■Your complete medical history, especially cardiovascular health
• ■All current medications, especially nitrates or blood pressure medications
• ■Any previous experience with ED treatments
• ■Your health goals and expectations