Semaglutide
Semaglutide is a prescription medication that acts on GLP-1 receptors to support blood sugar management and weight management in adults with qualifying conditions.
Why people explore this treatment
- ■Chronic weight management in adults with qualifying criteria
- ■Blood sugar management in adults with type 2 diabetes
What It Is
Semaglutide is an FDA-approved prescription medication belonging to a class of drugs called GLP-1 receptor agonists. It is approved for the treatment of type 2 diabetes and for chronic weight management in adults with qualifying criteria.
How It Works
Semaglutide works by mimicking GLP-1, a naturally occurring hormone that affects appetite, digestion, and blood sugar regulation. This may help reduce appetite and improve metabolic function.
Clinical Uses
- ■Chronic weight management in adults with qualifying criteria
- ■Blood sugar management in adults with type 2 diabetes
Available Formulations
- ■Once-weekly subcutaneous injection
- ■Daily oral tablet
Potential Benefits
- ■May support weight management in qualifying adults
- ■May help improve blood sugar control
- ■Available as injection or oral tablet
Risks & Considerations
- ■Not appropriate for patients with personal or family history of certain thyroid cancers
- ■Not appropriate for patients with history of pancreatitis
- ■Should not be used during pregnancy
Potential Side Effects
- ■Nausea
- ■Diarrhea
- ■Vomiting
- ■Constipation
- ■Decreased appetite
- ■Injection site reactions
Who May Not Be a Candidate
- ■Patients with personal or family history of medullary thyroid carcinoma
- ■Patients with Multiple Endocrine Neoplasia syndrome type 2
- ■Patients with history of pancreatitis
- ■Pregnant or breastfeeding women
Monitoring & Labs
- ■Blood glucose / HbA1c
- ■Kidney function
- ■Lipid panel
- ■Thyroid function as indicated
Regulatory / Clinical Status
FDA-approved for type 2 diabetes and chronic weight management in adults with qualifying criteria.
How It Is Administered
Semaglutide is available as a once-weekly subcutaneous injection or a daily oral tablet. Your provider will determine the appropriate form and dosing.
What to Discuss With Your Provider
- ■Your complete medical history, including any history of thyroid conditions or pancreatitis
- ■All current medications and supplements
- ■Any previous experience with GLP-1 medications
- ■Your health goals and expectations
Compare related options
Explore how this treatment relates to other options. No treatment is universally better — your provider can help determine what may be appropriate for your situation.
Frequently Asked Questions
Common questions about this treatment. For personal medical guidance, speak with a licensed provider.
Want to discuss this treatment with a provider?
Start a consultation to discuss whether this treatment or another option may be appropriate for your health goals. Treatment is subject to clinical evaluation and is not guaranteed.